New Molecular Solutions in Research and Development for Innovative Drugs

Lectures

Lectures list and abstracts.

Walter Keller

  1. Structural Biology of Allergens and Structure-based Epitope Mapping
  2. Structure and Function of a Bacterial Type IV Secretion System (T4SS)

Mario Cindrić

  1. De novo sequencing: From Edman to mass spectrometry

Boris Maček

  1. Principles of “shotgun” proteomics and proteogenomics
  2. Detection of kinase substrates using quantitative phosphoproteomics

Michael Przybylski

  1. Affinity - MS methodology
  2. Application of affinity - and ion mobility - MS to protein misfolding aggregation

Stefan Lichtenthaler

  1. Secretomics – principles of secretome analysis by mass spectrometry
  2. Degradomics – Proteomic Identification of protease substrates in vitro and in vivo

Michał Dadlez

  1. Mass spectrometry for protein structure studies – selected applications

Evgenij Fiskin

  1. Quantitative analysis of host immune response against bacterial infection

De novo sequencing: From Edman to mass spectrometry

Mario Cindrić, Ruđer Bošković Institute.

Degradomics – Proteomic Identification of protease substrates in vitro and in vivo

Stefan Lichtenthaler, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany

Detection of kinase substrates using quantitative phosphoproteomics

Boris Maček, Proteome Center Tuebingen

Mass spectrometry for protein structure studies – selected applications

Michał Dadlez, Laboratory of Mass Spectrometry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB-PAS), Warsaw, Poland

Principles of “shotgun” proteomics and proteogenomics

Boris Maček, Proteome Center Tuebingen

Quantitative analysis of host immune response against bacterial infection

Evgenij Fiskin, Tihana Bionda, Sjoerd van Wijk, Christian Behrends and Ivan Đikić. Institute of Biochemistry II, Goethe University School of Medicine and Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt

Secretomics – principles of secretome analysis by mass spectrometry

Stefan Lichtenthaler, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany

Structural Biology of Allergens and Structure-based Epitope Mapping

Walter Keller, Institut für Molekulare Biowissenschaften, Karl Franzens Universität

Structure and Function of a Bacterial Type IV Sectretion System (T4SS)

Walter Keller, Institut für Molekulare Biowissenschaften, Karl Franzens Universität

Uncovering molecular details of protein "misfolding - aggregation" using affinity- and ion mobility- mass spectrometry - Physiological and “Parkinson”- Synucleins

Michael Przybylski, Department of Chemistry and Steinbeis Research Center for Biopolymer Chemistry & Biomolecular Mass Spectrometry, University of Konstanz