Overview

9:00 Introduction  

1st Group

CD/LD spectropolarimetry

a) DNA and protein structure characterisation

b) Study of DNA/protein/ligand interaction – affinity, kinetics, structural aspects of complexes

Viscometry

Ligand binding mode impact on viscosity of biomacromolecule solution

2^nd Group

Microcalorimetry

a) Isothermal titration microcalorimetry: binding affinity, kinetics

b) Differential scanning microcalorimetry: structural characterisation